*Corresponding Author : Dr. Hamid Reza Edraki Rare Diseases Foundation of Iran (RADOIR), Iran Tel: +98-912-130-1258, E-mail: firstname.lastname@example.org
Received: August 16, 2018 Accepted: September 27, 2018 Published: October 01, 2018
Citation:Edraki HR (2018) Fetal MRI in Early Diagnosis of Rare Disease in Brain. J Immunol Tech Infect Dis 7:2. doi: 10.4172/2329-9541.1000163
A practical hands-on approach for using MRI techniques is provided to promote further fetal pathological conditions. This method of prenatal MRI diagnosis is done through the available literature revision. Apart from the findings and artifacts and numerous high-quality illustrations, the implications of fetal MRI based on medico-legal and ethical viewpoints has increased significantly
Managing Director at Rare Diseases Foundation of Iran (RADOIR)
The state of medical imaging in detecting COVID-19 patients is of high value. The CT scan without contrast media injection as the proposed method in diagnosis during treatment. In some cases, HRCT of lung references is recommended for higher penetration and finer levels, but epidemic and pandemic as well as the high range of X-ray exposition, applying the same method is to be investigated.
The most common sign and symptom of COVID-19 will be ground glass opacity (GGO) of lowers lobes of lungs and specially posterior and lateral segments in lungs in neighboring of chest thoracic wall or pleural cavity which is usually observed 5 days after disease appearance. Since the volumetric mass of the virus is very high and penetrates in lower areas and ends up to infectious and inflammatory changes.
Apart from this important symptom, there are other signs as haziness, consolidation, fibrotic band, crazy paving, speculation of the lesion.
In COVID-19 patients, the pleural effusion or lymphadenopathy are rare, active haziness of developed lobar will turn into bronchopneumonia and interstitial pneumonia which are finally called as white lung.
The simple lung CT scan and not HRCT, the amount of radiation and shorter time left to HRCT. In some centers, 3D methods are also used which are of more value rather than 2D’s. During CT scan, the patient takes a deep breath (deep inhale) and keeps till the end of test and delicate axial cuts later on. The simple radiography of lungs (even digital) is of no value in diagnostic pulmonary involvement with COVID-19.
In the following table, the diagnostic protocol of COVID-19 in CT scan confirmed by The Radiological Society of North America (RSNA) and National Institute of Health (NIH), has been presented.
Rare Diseases Europe, an alliance of over 800 rare disease patient organisations, is today urging Member States of the EU to take off the table the proposal of the Presidency of the EU Council to withdraw Article 7 of the current proposal for European cooperation on health technology assessment (HTA).
At a recent meeting of the Council of the International Society for Neonatal Screening, it was decided that the organization would present a plaque to Dr. Louis I Woolf recognizing his seminal contributions to the treatment of phenylketonuria, which made possible, and required the development of neonatal screening for maximum effectiveness.
Patient recruitment has always been challenge for companies conducting clinical trials. Knowing how to properly engage with advocacy groups can determine whether they will treat you as a trusted partner or a necessary evil.
Using both CRISPR-Cas9 and base editor 3 (BE3) gene-editing tools, the team reduced cholesterol levels in healthy mice treated in utero by targeting a gene that regulates those levels. Also used prenatal gene editing to improve liver function and prevent neonatal death in a subgroup of mice that had been engineered with a mutation causing the lethal liver disease hereditary tyrosinemia type 1 (HT1).
The researchers were able to trace the origin of CAID by using Quebec’s BALSAC genealogical database. Their goal was to predict in which parts of the province the disease is most likely to appear in future generations, depending on the areas where there are the greatest numbers of carriers of the recessive gene that causes the disease. They believe this information may help the medical system save money on CAID testing in future.
In a study at seven hospitals across the UK and the USA, researchers found the brain scan, called magnetic resonance (MR) spectroscopy. Brain damage affects around one in 300 births in the UK, and is usually caused by oxygen deprivation.
Since it can take 5 to 7 years for a patient with a rare disease to receive an accurate diagnosis—which can be the gateway to appropriate treatments and access to life-saving clinical trials—a panel at this year’s National Organization of Rare Diseases’ Rare Diseases & Orphan Products Breakthrough Summit (NORD Summit) held in Washington, DC, delved into specific associated challenges and how providers might overcome them.